Thurman joins a previously announced cast that includes, Charlotte Gainsbourg, Shia LaBeouf, Stellan Skarsgard, Jamie Bell, Stacy Martin, Connie Nielsen and Christian Slater.
Gainsbourg will star as Joe, a self-diagnosed nymphomaniac. Skarsgard will play Seligman, an old, charming bachelor who finds Joe beaten up in an alley. He takes her home to care for her, and Joe recounts to him the story of her erotic life, from birth to the age of 50.
The film will be split into two parts, with von Trier shooting a softer and more explicit version.
Source: The Hollywood Reporter